Research Technician Iii - Toronto, Canada - University Health Network

Sophia Lee

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Sophia Lee

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Description

Research Technician III

Job Posting #: 929002

Union:
Non-Union


Site:
Krembil Research Institute


Department:
Donald K. Johnson Eye Institute


Reports to:
Dr. Brian Ballios


Hours:35 hours per week


Wage range:
$ $44.16 hourly. To commensurate with experience and consistent with UHN compensation policy


Status:
Temporary Full-Time


Shifts:
Day


Posted Date:
February 22, 2024


Closing Date:
March 23, 2024


The University Health Network, where "above all else the needs of patients come first", encompasses Toronto General Hospital, Toronto Western Hospital, Princess Margaret Cancer Centre, Toronto Rehabilitation Institute and the Michener Institute of Education.

The breadth of research, the complexity of the cases treated, and the magnitude of its educational enterprise has made UHN a national and international resource for patient care, research and education.

With a long tradition of ground breaking firsts and a purpose of "Transforming lives and communities through excellence in care, discovery and learning", the University Health Network (UHN), Canada's largest research teaching hospital, brings together over 16,000 employees, more than 1,200 physicians, 8,000+ students, and many volunteers.

UHN is a caring, creative place where amazing people are amazing the world.


Position Summary:


The Krembil Research Institute at the University Health Network (fully-affiliated with the University of Toronto) has an opening for a temporary full-time, Research Technician in the laboratory of Dr.

Brian Ballios. This position is available for a one-year contract with possibility for renewal.

Dr. Brian Ballios is an Assistant Professor at the University of Toronto, and a Clinician-Scientist in the Donald K. Johnson Eye Institute at the University Health Network, as well as a Scientist at the Krembil Research Institute. He is a specialist in acquired and inherited retinal disease and ocular genomics.

Our laboratory work is focused on:
[1] Understanding the pathobiology of retinal disease, by establishing translational models of retinal degeneration;
[2] Discovering new therapeutics to treat retinal disease, using retinal and stem cell biology;
[3] Integrating new technologies, to enhance the performance of cell-based retinal therapies; and,

[4] Developing preclinical technologies to translate to first-in-human clinical studies


The overall goal of our work is to cure retinal blindness by discovering new therapies for inherited and acquired disease.


Duties

Including, but not limited to:

  • Maintaining cell lines (cultured and primary), including multipotent and pluripotent stem cell cultures, using standard sterile techniques
  • Conduct experiments to support ongoing lab research projects (Western blots, qRTPCR, immunocytochemistry and immunohistochemistry)
  • Conduct and assist with in vivo experiments in animal models of disease (drug and cell injections and transplantation), as well as necropsy and dissection for primary cell isolation
  • Coordinate the collection and organization of patient samples for stem cell derivation
  • Support the daytoday operations of the laboratory
  • Assist the research team on daily lab tasks
  • Help develop standard operating procedures and protocols for labrelated activities

Qualifications

  • Minimum of a Bachelors degree in biological sciences, or equivalent discipline
  • 6 years of related experience is required
  • Mandatory prior experience with standard laboratory protocols for cell culture, Western blot, qRTPCR, DNA electrophoresis and genotyping, molecular cloning
  • Prior experience with primary cell isolation from tissue specimens (animals or human) is an asset
  • Prior experience with animal models of disease is an asset
  • Viral transduction and genetic engineering / geneediting (e.g., CRISPR/Cas9) experience is an asset
  • RNA sequencing and bioinformatics experience is an asset
  • Willing to rapidly learn new techniques and skills with training
  • Capacity to work independently with mínimal supervision
  • Highly organized and able to prioritize effectively
  • Able to communicate and interact with staff, students, colleagues in a clear and professional manner
  • Flexible to work occasional evenings and/or weekends

Why join UHN?


In addition to working alongside some of the most talented and inspiring healthcare professionals in the world, UHN offers a wide range of benefits, programs and perks.

It is the comprehensiveness of these offerings that makes it a differentiating factor, allowing you to find value where it matters most to you, now and throughout your career at UHN.


  • Competitive offer packages
  • Close access to Transit and UHN shuttle service
  • A flexible work environment
  • Opportunities for development and promotions within a large organization
  • Additional perks (multiple corporate discounts including: travel, restaurants, parking, phone plans, auto insurance discounts, onsite gyms, etc.)
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