- Leading internal preclinical in vivo pharmacology studies to support programs around different disease indications
- Designing, supporting execution, and interpreting in vivo pharmacology studies to generate proof-of-concept data and build confidence in selection of molecules for clinical development
- Evaluating available data sets to identify animal models, build testable biological hypotheses for new targets, and then preclinically assessing those hypotheses
- Work closely with the internal teams and/or external CROs, to effectively and efficiently execute in vivo preclinical studies
- Collaborating with cross-functional project teams within protein engineering, in vitro biology, pharmacokinetics, modeling, and biomarkers to identify lead molecules and advance programs to human clinical trials
- Supporting and mentoring in vivo pharmacology teammates by providing scientific expertise and practical support during preclinical study design, execution, and data analysis
- Collaborating with the project team and teammates on regulatory documents to support regulatory filing
- Reporting findings to program teams and senior leadership to support data-driven decisions
- You have a strong background in preclinical drug development of biologics in an industry setting, including discovery, identification and establishment of animal models, in vivo pharmacology, and efficacy in disease models
- You have experience in oncology, immunology, or pain (desirable); scientific expertise in other disease areas will also be considered
- You have a PhD in pharmacology, immunology, or a related field, plus at least 8 years of experience in a biopharmaceutical industry setting; candidates with a MSc and 12+ years of relevant industry experience will also be considered
- You have proven interpersonal skills and create value on cross-functional teams
- You are genuinely curious, with an interest in discussing innovative ideas in a highly collaborative and fast paced environment
- You are good at communicating scientific and/or technical concepts with an emphasis on application
- You are able to independently identify project needs and follow that up with constructing and implementing solutions
- You enjoy the teamwork that comes with working on complicated biological questions and building data sets that help to predict the success of therapies
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We are looking for an experienced, strategically minded Principal Scientist to join our expanding Non-Clinical Safety team based in Vancouver, Canada.How You Might Spend Your DaysLeading the planning, design, execution and and interpretation of nonclinical toxicology programs in ...
Vancouver, British Columbia2 weeks ago
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We are looking for an experienced strategically minded Principal Scientist to join our expanding Non-Clinical Safety team based in Vancouver Canada You will be responsible for designing planning monitoring and reporting of non-GLP and GLP toxicology studies and provide nonclinica ...
Vancouver, BC2 weeks ago
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We are looking for an experienced, strategically minded Principal Scientist to join our expanding Non-Clinical Safety team based in Vancouver, Canada. You will be responsible for designing, planning, monitoring and reporting of non-GLP and GLP toxicology studies and provide noncl ...
Vancouver $134,000 - $168,000 (CAD) Full time2 weeks ago
- Work in company
Principal Scientist/Senior Principal Scientist, CMC, Analytical Chemistry
Only for registered members
Xenon Pharmaceuticals (NASDAQ:XENE) busca a un · Principal/Senior Principal Scientist, · Cornica Analítica para desarrollar metodologías analíticas y actividades de caracterización.Lead a team of scientists and research associates supporting the development of New Chemical Entit ...
Vancouver, British Columbia3 weeks ago
- Work in company
Principal Scientist/Senior Principal Scientist, CMC, Analytical Chemistry
Only for registered members
We are seeking a Principal/Senior Principal Scientist,CMC ,Analytical Chemistry to join our team.This position will report to the Executive Director,CMC ,Analytical Development and will be responsible for the development of analytical methodology and characterization activities i ...
Vancouver $150,500 - $211,900 (CAD)1 month ago
- Work in company
Principal Scientist/Sr. Principal Scientist, CMC, Analytical Chemistry
Only for registered members
Xenon Pharmaceuticals is looking for a Principal/Senior Principal Scientist, CMC, Analytical Chemistry to join their team. The successful candidate will be responsible for the development of analytical methodology and characterization activities in support of new drug substance a ...
Burnaby Full time1 week ago
- Work in company
Principal Scientist/Sr. Principal Scientist, CMC, Analytical Chemistry
Only for registered members
We are seeking a Principal/Senior Principal Scientist, CMC, Analytical Chemistry. · This position will report to the Executive Director, CMC, Analytical Development and will be responsible for the development of analytical methodology and characterization activities in support of ...
Burnaby $150,500 - $211,900 (CAD)1 week ago
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+We are seeking a senior or principal structural geologist for our Vancouver-based geology team. · +Belt-to-deposit-scale structural analysis and interpretation of mineralized systems · + · A postgraduate degree specializing in the structural geology of ore deposits, preference f ...
Vancouver, British Columbia2 weeks ago
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The UBC CDC is hiring a Research and Development Senior Assistant to support various research programs and projects associated with the Viral Immune Responses Lab. · ...
Vancouver, BC1 week ago
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The Pacific Parkinson's Research Centre is seeking a full-time Clinical Research Assistant to join our multidisciplinary research team. In this role, you will play a vital part in advancing our studies by using your strong communication skills to recruit and engage with research ...
Vancouver, BC1 month ago
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This is a regular full-time staff position and a non-academic option for Research Associates who have completed their term(s) at PHSA and are transitioning from the academic path to begin conducting scientific research outside the academic research stream. · ...
Vancouver1 week ago
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We are seeking a Research Scientist to join our CMC team. The ideal candidate will work flexibly across a number of small molecule drug development programs with an emphasis on the development of in-house analytical methods on new research/development compounds that will be subse ...
Vancouver, BC, Canada1 week ago
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The Stewart Blusson Quantum Matter Institute (Blusson QMI) at UBC is a world-leading venture into research of systems and phenomena involving quantum science. · ...
Vancouver, BC1 month ago
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This is a regular full-time staff position at BC Cancer Research Institute. · A level of education, training and experience equivalent to a Ph.D. in a related scientific field plus five (5) years of recent, relevant post-doctoral research experience. · ...
Vancouver, British Columbia4 days ago
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We're looking for a Principal Consultant -Java, Selenium, and API automation at Genpact who will build the future with AI. · At Genpact we don't just adapt change-we drive it.AI digital innovations redefine industries, · and we lead the charge.Enjoy solving real-world problems be ...
Canada Vancouver, CA1 month ago
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We are the home of ambitious, passionate, and innovative world shapers.The Opportunity · Innovate and Lead – This is your opportunity to shape the future of mine waste engineering. · ...
BC, Canada1 week ago
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The UBC CDC is hiring a Research and Development Senior Assistant to support the various ongoing research programs and projects associated with the Viral Immune Responses Lab.Manage laboratory finances in collaboration with senior scientists. · Liaise with collaborators regarding ...
Vancouver $5,365 - $7,709 (CAD) Part time1 week ago
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To perform scientific research, · specifically research activities related to X-ray crystallography and bioinformatic analysis of proteins and to report results ready for publication and/or use for grant applications as appropriate. · , · , , ...
Vancouver, BC1 month ago
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We are looking for a driven and collaborative engineer who will directly contribute to a new front-end Photos experience from Microsoft. · Owning large features and contributing to the overall architectural vision of the application. · PARTNERING closely with your counterparts in ...
Vancouver, BC1 month ago
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The Cancer Exercise & Physiotherapy Lab is seeking a Postdoctoral Research Fellow to perform research on assessment of sarcopenia, cachexia and body composition changes in people with GI cancers. · Coordinating research activities and manage project timelines · Leading the develo ...
Vancouver, BC $50,000 - $80,000 (CAD) per year3 days ago
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Build the Future With Us — In this Principal Hydrotechnical Engineer role, you'll apply your technical leadership to meaningful projects shaping water systems and resilient communities across British Columbia. · From watershed modelling to complex hydraulic analysis, you'll contr ...
Vancouver, BC, Canada1 week ago
Principal Scientist - Vancouver - AbCellera
Description
1 day ago Be among the first 25 applicants
From target to the clinic. AbCellera's platform integrates biology, computation, and engineering to develop impactful antibody-based medicines. We're scientists, engineers, and business professionals who work together to turn scientific insights into breakthrough medicines. We pursue truth and scientific rigor. We think independently, act with conviction, and have the courage to work at the edge of the unknown. We offer the opportunity to stretch and explore, and to work on things that matter.
How You Might Spend Your Days
We'd love to hear from you if
What We Offer
AbCellera's hiring range for this role is CAD $135,000 - $168,600 annually, commensurate with your education and job-related knowledge, skills, and experience. In addition to base salary, we offer equity, annual bonus dependent on team and company performance, and a 6% (non-match) RRSP contribution.
You will have a CAD $1,500 annual Active Lifestyle Allowance, annual vacation, professional development opportunities, and comprehensive health benefits. Scientific and technical mentorship is a priority. And you'll find we prioritize teams and social groups to build community and connections across AbCellera.
About AbCellera
AbCellera is a global company focused on delivering breakthrough medicines that alleviate suffering, extend lives, and improve health. Our platform includes fully integrated capabilities to create first-in-class and best-in-class antibody medicines, from discovery to clinical manufacturing.
We are using our technological advantage to develop programs across multiple indications including endocrine and metabolic conditions, oncology, and inflammation and autoimmunity. We're advancing programs involving complex transmembrane proteins, bispecifics, and antibody drug conjugates.
Creating medicines is the most important work we can do. When tenacious people share a vision and work together, they can truly have a positive impact. That's why we hire for character and intelligence, not just for CVs or experience.
We look for people with drive and energy. People we trust. People who need to know their days are being well spent. That their work really matters. In the end, our success will be measured by the impact of our medicines.
To apply
Please submit your application through our website and refer to Job ID 23323 in your cover letter. We apologize in advance, but we receive a large volume of applications and are only able to contact those who are selected for an interview. All communication from our Talent Discovery team will come from an email address.
Referrals increase your chances of interviewing at AbCellera by 2x
Get notified about new Principal Scientist jobs in Vancouver, British Columbia, Canada.
Seniority level: Mid-Senior level
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Principal Scientist
Only for registered members Vancouver, British Columbia
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Principal Scientist
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Principal Scientist
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Principal Scientist/Senior Principal Scientist, CMC, Analytical Chemistry
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Principal Scientist/Senior Principal Scientist, CMC, Analytical Chemistry
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Principal Scientist/Sr. Principal Scientist, CMC, Analytical Chemistry
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