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    Manager, BSL2 Protein Production Laboratory - VancouverUBC, Canada - University of British Columbia

    University of British Columbia
    University of British Columbia VancouverUBC, Canada

    4 weeks ago

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    Description


    Staff – Non Union

    Job Category
    M&P – AAPS

    Job Profile
    AAPS Salaried – Research and Facilitation, Level C

    Job Title
    Manager, BSL2 Protein Production Laboratory

    Department
    Strynadka Laboratory Department of Biochemistry and Molecular Biology Faculty of Medicine

    Compensation Range
    $6,551.00 – $9,418.83 CAD Monthly

    The Compensation Range is the span between the minimum and maximum base salary for a position. The midpoint of the range is approximately halfway between the minimum and the maximum and represents an employee that possesses full job knowledge, qualifications and experience for the position. In the normal course, employees will be hired, transferred or promoted between the minimum and midpoint of the salary range for a job.

    Posting End Date
    November 29, 2023

    Note: Applications will be accepted until 11:59 PM on the day prior to the Posting End Date above.

    Job End Date

    At UBC, we believe that attracting and sustaining a diverse workforce is key to the successful pursuit of excellence in research, innovation, and learning for all faculty, staff and students. Our commitment to employment equity helps achieve inclusion and fairness, brings rich diversity to UBC as a workplace, and creates the necessary conditions for a rewarding career.

    Job Summary
    The Laboratory of Dr. Natalie Strynadka is currently seeking to hire a Manager, BSL2 Protein Production Laboratory with strong molecular biology and membrane protein production skills to manage a BSL2 protein production facility at the University of British Columbia (UBC) within the Life Sciences Institute located on the Vancouver campus. Funded through the Canada Foundation of Innovation and other national funding programs, our research is focused on exploring frontiers in structural biology, with the central goal of accelerating the development of effective therapeutic agents. The research program is highly interdisciplinary, capitalizing on collaborations cross institute, cross UBC as well as nationally and internationally and spanning both the academic and industrial sectors. The Laboratory Manager will be responsible for managing and overseeing multi-disciplinary facility research projects both internally and collaboratively. This includes designing, overseeing, and ensuring efficient execution of projects within set timelines and budgets. The role also involves providing operational oversight, scheduling and maintenance expertise for an extensive suite of molecular biology and protein production equipment for both prokyaryotic and eukaryotic cell expression and isolation, including customized procedures for membrane proteins.
    Organizational Status
    The incumbent reports to the Principal Investigator, Dr. Natalie Strynadka and works closely with the other researchers and stakeholders engaged with the research program.
    Work Performed

    Management, coordination, and communication for all multi-disciplinary facility research projects (internal projects and external collaborative research)

    • Design, develop and oversee research projects, collaborating with academic and industry groups and ensure the projects are executed efficiently, on time, and within budget.
    • Collaborate on the development of strategic research plans and facilitate the development of contracts and research agreements.
    • Develop and manage contract budgets, communications and formal reports on research progress and facility usage.
    • Develop documentation and obtain necessary approvals, including development and submission of facility safety certificate applications, material and data sharing agreements.
    • Provide strategic guidance to researchers, staff and trainees, identifying opportunities for improvement and offering solutions to research challenges.
    • Plan and coordinate sample submissions for all facility research projects.
    • Implement research strategic goals and objectives of the user group by ensuring resources are available to achieve goals.
    • Provide expertise, direction and technical knowledge to staff in the BSL2 protein suite on cutting edge molecular biology and protein production techniques, as well as consultation on project work, specimen preparation and data collection support for internal and external collaborative research projects.
    • Coordinate meetings with key stakeholders to disseminate data, discuss recommendations on research methodology and facilitate consensus.
    • Create and establish new research collaborations.

    Oversee the day-to-day operation of the BSL2 protein production facility

    • Schedule maintenance, devolve and execute safe operation guidelines.
    • Coordinate advanced service with the varied service engineers to ensure optimal performance of the equipment.
    • Supervise and train BSL2 protein production suite support staff and facility users to ensure safe, efficient use and functionality of the facility.
    • Forecast and report budget requirements for facility expenses, inventory acquisition, as well as use and research productivity of the various instruments.

    Other Responsibilities

    • Assist in writing, reviewing and submitting research publications and grant applications in conjunction with facility researchers.
    • Perform other related duties as required.

    Consequence of Error/Judgement
    The incumbent must consistently exercise sound judgement and discretion in the overall coordination and management of research projects. The impact of decisions and consequence of error is significant. It is of the utmost importance to maintain confidentiality, diplomacy, integrity, and security of study data. Errors or omissions in research procedures, analyses, or ineffective mentorship could lead to loss of partner relationships, funding or decisions that adversely affect the effectiveness and reputation of the program.
    Supervision Received
    The position works independently under broad directives from the Principal Investigator, Dr. Natalie Strynadka.
    Supervision Given
    The Manager, BSL2 Protein production facility, in consultation with the PI, will provide general direction to and supervision of research assistants, trainees and scholars in the research lab. The individual may supervise more junior staff that support facility operations.
    Minimum Qualifications
    For research work, a post-graduate degree or equivalent professional designation with a minimum of four years of related experience, or an equivalent combination of education and experience. Otherwise, an undergraduate degree in a relevant discipline is required with a minimum of six years of related experience, or an equivalent combination of education and experience.
    – Willingness to respect diverse perspectives, including perspectives in conflict with one's own

    – Demonstrates a commitment to enhancing one's own awareness, knowledge, and skills related to equity, diversity, and inclusion

    Preferred Qualifications

    • MSc and/or professional degree in a relevant discipline, preferably post-graduate level.
    • Experience in the management, operation and maintenance of infrastructure and methods requisite to molecular biology and both prokaryotic and eukaryotic protein overexpression/purification in a BSL2 environment with a particular emphasis on membrane proteins and membrane protein assemblies.
    • Preferred experience in facility management activities including basic and advanced training and evaluation of users in the BSL2 protein production workflow, supervision of personnel, resource management, and vendor engagement are desired.
    • Experience in analysis of biological systems for protein overexpression.
    • Demonstrated competency in academic or technical writing and communication.
    • Ability to manage effectively in a dynamic environment which requires multi-tasking, and working effectively under pressure to meet deadlines.
    • Possess strong time management and organizational skills.
    • Ability to prioritize and work effectively under pressure to meet deadlines.
    • High-level interpersonal communications skills and the ability to liaise with staff and research students, professional/technical staff, industrial collaborators, vendors and service engineers.
    • Proficiency in the use of relational databases for sample submission and inventory tracking.
    • Knowledge of university policies, procedures, governance and administrative systems for research conducted in a university setting, including ethical requirements.
    • Ability to successfully foster and maintain relationships with diverse external stakeholders.
    • Ability to communicate with diplomacy, tact, and integrity in both verbal and written communication.

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