Research Associate in Tuberculosis Drug Discovery - Vancouver, Canada - UBC

UBC

Verified Company

Vancouver, Canada

1 day ago

Posted by:

Sophia Lee

beBee Recruiter

Description

Academic

Job Category
Faculty Non Bargaining

Job Title
Research Associate In Tuberculosis Drug Discovery

Department
Av-Gay Laboratory Division of Infectious Diseases | Department of Medicine | Faculty of Medicine (Yossef Av-Gay)

Posting End Date

Note:
Applications will be accepted until 11:59 PM on the day prior to the Posting End Date above.

Job End Date
Jun 2, 2026

The expected pay for this position is $68,932/annum (prorated: 27,

A research associate position is available in Professor Yossef Av-Gay's laboratory at UBC Department of Medicine, Division of Infectious Diseases.

Research Description:

Mycobacterium tuberculosis (Mtb), the etiological agent of tuberculosis (TB), is one of the most devastating infectious agents in the world.

One third of the world's population is exposed to Mtb, which kills nearly two million people annually. With the increasing prevalence of drug-resistant TB, there is a pressing need for better and new drugs against Mtb.

Macrophages are key components of the human innate immune system with a defined role of seeking and destroying invading microorganisms.

Mtb, however, can neutralize the macrophage's killing machinery. While isolated inside the phagosomes, Mtb avoids key components of the host immune system.

As such, TB disease progression relies on the intimate interaction between the host macrophage and the invading microbe whereby recognition, control and elimination of Mtb are mediated by host signal transduction proteins.

Qualifications:

5 years prior experience in microbiological techniques, cell-based assays and medicinal chemistry or drug discovery
A Ph.
D. in Microbiology or Biochemistry (or related disciplines)
Related work experience and peer-reviewed publications
Strong oral and proven written communication skills
Excellent organization skills and be able to work effectively within a team environment

Responsibilities will include, but will not be limited to:
Performing literature and systematic reviews related to TB drug development
Staying updated on literature advancing the emerging science of causes and related strategies, to treat infectious diseases.
Performing High Throughput and High Content Screening Experiments.
Performing Biochemical and genetic validation studies
Coordinating external experiments
Developing reports and manuscripts for publication
Preparing and delivering presentations for research meetings
Providing other support as required to Av-Gay's lab team

Supervision