Postdoctoral Research in Breast Cancer Metastasis - Montréal, Canada - Springer Nature

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Description

Postdoctoral Research in Breast Cancer Metastasis:

Employer
IRCM-Côté laboratory
Location
Montréal, Quebec (CA)
Salary
minimum 45 000$ (CAD)
Closing date
5 Apr 2024
Discipline

Biomedicine, Health Science
Job Type
Postdoctoral
Employment - Hours
Full time
Duration
Fixed term
Qualification
PhD
Sector
Academia- You need to sign in or create an account to a job.

Job Details
Company

Job Details:

POSTDOCTORAL RESEARCH TO STUDY THE ROLE OF THE AXL RECEPTOR TYROSINE KINASE IN CELLULAR TRAFFICKING AND IN BREAST CANCER METASTASIS
The IRCM's Cytoskeletal Organization and Cell Migration Research Unit, headed by Dr.

Jean-François Côté, Canada Research Chair in Cellular Signaling and Cancer Metastasis, is seeking to recruit a postdoctoral researcher to carry out a project on the AXL kinase, aimed at defining its role in cell trafficking and the metastatic cascade of breast cancer.

This project is funded by the Canadian Institutes of Health Research (CIHR). The Côté laboratory has an internationally recognized expertise in cell signaling and cancer biology.

Targeting Axl favors an antitumorigenic microenvironment that enhances immunotherapy responses by decreasing Hif-α levels

_PNAS_ USA 2021 (PMID:

AXL confers cell migration and invasion by hijacking a PEAK1-regulated focal adhesion protein network

_Nature Communications_ 2021 (PMID:

Mapping the proximity interaction network of the Rho-family GTPases reveals signalling pathways and regulatory mechanisms.

_Nature Cell Biology _2020 (PMID:

The receptor tyrosine kinase AXL is required at multiple steps of the metastatic cascade during HER2-positive breast cancer progression

_Cell Reports_ 2018 (PMID:

Summary of responsibilities**
Financial support and duration of contract

Qualifications required
PhD in biochemistry, biology or molecular biology (or related field);
At least one manuscript published or in preparation (e.g. bioRixv) as first author;
Independence, autonomy and productivity in laboratory experiments; Ability to generate new research hypothesis to answer the project's scientific questions and to bring the project to fruition;
Fluency in English (written and verbal);

The IRCM at a glance
The IRCM is located at the corner of rue St-Urbain and avenue des Pins, near downtown and Plateau Mont-Royal. The Place-des-Arts (green line) and Sherbrooke (orange line) metros are a 10-minute walk away. We are connected by several bike paths, including those on rue St-Urbain and avenue des Pins. We have secure bicycle parking. There are also several parking lots in the area offering reasonably priced daily and monthly packages. The IRCM is an autonomous, not-for-profit research institution, affiliated with the Université de Montréal and associated with McGill University. In addition, the Institute's clinic is associated with the Centre hospitalier de l'Université de Montréal (CHUM).

All IRCM researchers hold university appointments at the Université de Montréal, and most research directors are also associate members of McGill University.

Located in the heart of Montreal's academic community, the IRCM attracts the best researchers.

Every year, more than a hundred master's and doctoral students, as well as some fifty postdoctoral fellows, supervised by experienced researchers in various fields of biomedical research, come to improve and/or polish their scientific training at the Institute.

The training of students, postdocs and employees is an integral mission of IRCM, and we aim to attract and retain the best scientists.

We have a dedicated academic affairs team with the primary mission of providing a respectful work environment and supporting all members of the IRCM community.

IRCM's Code of Collegial Conduct clearly specifies that respect for people and gender equality is a core value of our institution, and we recognize diversity as a strength and a source of richness.

IRCM strives to provide an environment that promotes and supports the inclusion and fair representation of women, members of the LGBTQ+ community, people living with disabilities and people from ethnic, cultural and religious minorities.

Company:

The laboratory of Dr. Jean-François is part of the Cancer Centre at the Clinical Research Institute of Montreal (IRCM).

Company info