Technician Ii - Toronto, Canada - Lunenfeld-Tanenbaum Research Institute

Lunenfeld-Tanenbaum Research Institute

Verified Company

Toronto, Canada

2 weeks ago

Posted by:

Sophia Lee

beBee Recruiter

Description

Reference Number:

Posted Date:6/13/2023

Closing Date:7/4/2023

Department:

LTRI

Position:
Technician II

POSITION TITLE

Technician II
DEPARTMENT
LTRI
EMPLOYMENT TYPE
Temporary, Full-Time
HOURS OF WORK
37.5 hours per week
EMPLOYEE GROUP
Non-Union
REPORTS TO
Prinicpal InvestigatorThe Department of Obstetrics and Gynaecology of Mount Sinai Hospital is one of the largest academic centres for women's health care in the country. In addition, the Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, a University of Toronto affiliated research centre, is one of the world's leading centres in biomedical research. With groundbreaking discoveries in research areas such as diabetes, genetic disorders, cancer and women's and infants' health, the Institute is committed to excellence in health research and the training of young investigators. Strong partnerships with the clinical programs of Mount Sinai Hospital ensure that scientific knowledge is used to promote human health. Your significant contributions will assist in maintaining our momentum in advancing our research.

JOB SUMMARY:

We have an immediate opening for a Research Technician in our lab, which is focusing on _in vivo_ gene manipulations esp.

using CIRSPR/Cas9 editing to delineate pathogenic mutations in various cancers and immune diseases.

The applicant would be responsible to provide specialized technical service including mouse colony management and animal experimentation and some tissue culture procedures such as virus production and concentration as well as Molecular Biology techniques such as basic cloning steps and qRT-PCR.

The Technician would be responsible for his/ her work and assist the investigator and trainees in the conduction of research and mouse procedures.

JOB RESPONSIBILITIES:

Responsible for basic animal husbandry duties for laboratory mice and responsible for their overall health and welfare. A variety of animal health care duties are required such as general husbandry including cage changing, health checks on all animals and identifying changes in animal health or deviations in normal behavior, plug checks, monitoring of for tumor growth. Working with a specialized colony management database and improving SOPs.
Conducts research experiments within the group and may have specialized expertise or knowledge in mouse colony management and experimentation.
Generate and maintain cell cultures for generation as well as production of hightitter viral preparations.
Performing ear tagging and genotyping.
Basic cloning steps.
Experience with mouse survival surgeries such as xenograft injections, tail vein injections, lung inhalations, ultrasoundguided injection, ultrasoundassisted embryo staging desirable.
Experience with tissue harvesting desirable.
Exercises considerable independent judgment, initiative and decision making in consultation with investigator to resolve matters relating to interpretation of test results, modification of techniques and procedures

EDUCATION & EXPERIENCE REQUIREMENTS:

Bachelor's with experience in related specialized area, Master's Degree would be considered an asset
Preference will be given to applicants who have 2 or more years experience in a research setting with proven technical and surgical abilities with rodents. Experience in mouse handling and mouse experimentation including survival surgeries would be ideal

FUNCTIONAL JOB REQUIREMENTS:

Must be able to exercise good judgment, exercise considerable independence and take initiative
Must possess exceptional communication skills (verbal, written and presentation) and be comfortable engaging and exchanging information with other members of the lab
Must be reliable, organized, and flexible with ability to handle multiple activities. to
Demonstrated analytical and problem solving abilities with strong attention to detail
Experience with project management
Demonstrated knowledge of standard software (e.g. LIMS, Microsoft Office Suite)
Must demonstrate satisfactory work performance and attendance record
To ensure the safety and wellbeing of all our people and patients, Sinai Health has made it a priority to support everyone in getting vaccinated against COVID19. Consistent with this, our Staff Immunization & Surveillance Policy was recently updated to include the requirement for full vaccination currently defined as receiving two doses and serving a 14day waiting period following the second dose in order to be able to work at Sinai Health. To be compliant with our updated Policy, you must provide proof of dual COVID19 vaccination, as indicated on the Prospective Immunization and Surveillance Policy Information Sheet, in order to be eligible for employment at Sinai Health. If you believe you are one of the very few people who may require an exemption from vaccination, supporting medical information must be submitted to our