Anthony Bruce

I am an outgoing, dedicated and highly capable sales associate.  I have strong personal skills, I am not shy and I am very emotionally intelligent. I want to be your next lynch pin. Hire me, you won't regret it!

Dear Sir/Madame, my name is Anthony Bruce, and I am writing to apply to the Medical Affairs position with your company. I have a strong and accomplished skill set to proficiently perform in this area. My previous experience in clinical research, medical writing, medical affairs and scientific research have taught me how to effectively work with cross-functional clinical, medical affairs, scientific and educational teams. I am a strong health, clinical and scientific thinker, with formidable analytical and organizational skills. 

As a PhD scientist and clinical research associate, I have a strong understanding in therapeutic development. Formerly, I have a BSc, MSc, PhD (all in molecular biology). Additionally, I am a clinical research associate (McMaster University), and I recently obtained my Board Certified Medical Affairs Specialist Certificate (BCMAS). I conducted my doctoral studies at St. Joseph`s Hospital, department of Urology and Nephrology, through the faculty of Medicine at McMaster University. I did a post-doctoral fellowship in breast cancer research at the University of Guelph, and a clinical research trial internship at the Pain Research Institute, at McMaster University. I also have my ICH-GCP and TCPS2 certifications. I am currently working on my HEOR/reimbursement certification, as well as business courses in the Quantic MBA program. 

I have published numerous scientific papers and given dozens of presentations to peers and faculty. I have also attended Research Ethics Board meetings at McMaster (HiREB). I have worked for a Medical Communications agencies developing medical and scientific educational content for pharmaceutical companies. Here I also supported Advisory Boards, gathering “actionable insights.” I have developed numerous copy decks for clients for medical education and communication. Moreover, I have written several SOPs for clinical trials protocols. I have also developed copy for numerous social media platforms such as LinkedIn, Twitter, email blasts, medical conference booths, and various banners. I recently learned PAAB and worked in a more regulatory affairs capacity. 

I have proven that I work well in a team or independently, to capably accomplish small- and large-scale projects, delivering goals in a timely manner. I easily contribute to valuable scientific exchanges in meetings. I hope that you find my skills and experience suitable for this position. Feel free to contact me anytime to further discuss my application and candidacy for this role.  

Sincerely  

Anthony Bruce BSc, MSc, PhD, CRA, BCMAS. 

TRAINING: 

PROJECT 1: Studied the role of microRNA clusters in primary epithelial mouse breast cancers and their loss in recurrent mesenchymal breast cancer tumors. 

PROJECT 2:  Studied the transcription factor Twist1 in primary epithelial mouse breast cancers (over expression) and its loss in recurrent mesenchymal mouse breast cancer.  

Courses include topics in coordinating clinical trials, ethics and regulatory affairs, methodologies, statistics, databases and internet use, as well as critical analysis of writing and communication in clinical trials. Also obtained ICH-GCP and TCPS2 certifications. 

Trained as an intern in clinical research for studies in pain research.  Experience with REDCAP software, organizing data, coding questionnaires in CONCEPT database, OHIP data entry, Pharmacy data entry, psychology database entry, Youth Pain patient`s data, DATACANN, and overall clinical research trials experience (April-Sept 2018). 

Completed the Board-Certified Medical Affairs Specialist Program, ACMA. Market Place Understanding, Brand Strategy Development, Scientific Communications Platform, Compliance Guidance, Gathering Actionable Insights, Innovative Medicines Code, Rules Governing Interactions with Healthcare professionals, Health Economics Outcomes Research, Evidence Based Medicine, Medical Information, Drug Development Process, Advisory Boards, Risk Evaluation and Mitigation Studies and more. 

Courses include: Customer Discovery, Finance, Marketing Fundamentals, Microeconomics-Supply and Demand, Accounting Fundamentals, One Variable Statistics, Blue Ocean Theory, Photography Basics, and Personal Investing (Stocks and Bonds). 

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EDUCATION: 

Location: St. Joseph`s Hospital Hamilton-Department of Urology and Nephrology 

PhD  PROJECT: Studied Cytochrome B5 Heme Binding Protein CYB5D2 and its Heme Binding Dependant Functions.   

Demonstrated that CYB5D2 confers survival from inhibition of PI3 Kinase, and that it interacts with endogenous Cytochrome P450 Reductase in serum starved conditions.  

Generated an Antibody to endogenous CYB5D2, and develped a dominant negative Heme Binding defective mutant (D86G), and shRNA knockdown stable cell lines.  

Demonstrated that Heme Binding was required for CYB5D2 to confer survival from chemotherapeutic agents ie Paclitaxol, Doxorubicin and Cisplatin. 

Recipient of a 3 Year Heart and Stroke Grant for work on CYB5D2 affects on cholesterol synthesis 

MSc PROJECT:  Studied the role and regulation of a serine/threonine kinase, GSK3β in v-src transformed Chicken Embryo Fibroblasts (CEFs). Generated stable cell lines expressing wt GSK3β, and dominant negative and a constitutively active version. Studied known substrates of 

GSK3β such as the transcription factor AP1 (c-fos and Jun) and Cyclin D1. Cloned and expressed Chicken CylcinD1 showing this as the substrate of GSK3β.