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    Postdoctoral Fellow and Research Associate - Winnipeg, Canada - University of Manitoba

    University of Manitoba
    University of Manitoba Winnipeg, Canada

    2 weeks ago

    University of Manitoba background
    Full time
    Description

    Rady Faculty of Health Sciences

    Max Rady College of Medicine Department of Pharmacology and Therapeutics

    A McDermot Avenue Winnipeg, MB, R3E 0T6



    Department of Pharmacology and Therapeutics Max Rady College of Medicine

    University of Manitoba

    Winnipeg, Manitoba, Canada

    The Pearson Lab is recruiting for a full-time term Postdoctoral Fellow and Research Associate to help lead our CIHR- and CCS-funded lung cancer projects to:

    (1) Explore the role of epigenetic plasticity and transcriptional reprogramming in lung cancer evolution and drug resistance.

    (2) Identify novel therapeutic strategies for the treatment of small cell lung cancer, the most aggressive form of lung cancer.

    To address these projects, our lab employs a multifaceted approach. We utilize a combination of in vitro approaches along with unique mouse genetic and xenograft models of lung cancer plasticity. This is coupled with leading-edge genomic, proteomic, CRISPR and single cell techniques. Together, this will allow us to better understand molecular mechanisms underlying the genesis and evolution of high-lethality lung cancers to identify novel therapeutic approaches to treat these cancers. For more info about the lab and these projects, please visit our website:

    Postdoctoral Fellow, Position # 34863

    The salary range for this position is $40,000 - $55,000 per annum (40 hours/week), commensurate with qualifications and experience, and will be for a 2-year term with possibility for extension.

    Research Associate, Position # 34864

    The salary range for this position is $50,000 - $70,000 per annum (40 hours/week), commensurate with qualifications and experience, and will be for a 2-year term with possibility for extension.

    The anticipated start date for these positions is June 1, 2024 or at a mutually agreed upon date.

    We are seeking individuals with a PhD in life sciences or related field with a background in molecular or cellular biology, cancer biology or genomics. Experience in the following areas is beneficial, but not essential:

    Mouse models (particularly lung and/or xenograft models) Genomics and bioinformatics CRISPR approaches (particularly those beyond traditional CRISPR knockout) Single-cell transcriptomics Spatial imaging and transcriptomics

    The successful candidates will join our multi-disciplinary team and work closely with bioinformatic collaborators and clinical oncologists at CancerCare Manitoba and the University of Manitoba. Located at the Paul Albrechtsen Research Institute within CancerCare Manitoba, our lab offers a unique setting to drive innovative research in close collaboration with clinician scientist and clinical oncologists. This provides an opportunity to rapidly translate discoveries to patient care through the clinical trials unit at CancerCare Manitoba.

    The Paul Albrechtsen Research Institute also receives generous support from the CancerCare Manitoba Foundation, which provides unique funding opportunities and access to state-of-the-art core facilities, such as the QuIPS platform ), which supports single cell genomics along with spatial and high-content imaging.

    Being located in Winnipeg, Manitoba will also allow the successful candidate to find an excellent work-life balance, which will allow them to help lead innovative translational research while also experiencing a high quality of life. As a moderately-sized Canadian city, Winnipeg offers the amenities of other large Canadian cities, but will allow you to avoid the exorbitant housing prices, high cost of living and long commute times that are unavoidable in most other major Canadian centers.

    The University of Manitoba is committed to the principles of equity, diversity & inclusion and to promoting opportunities in hiring, promotion and tenure (where applicable) for systemically marginalized groups who have been excluded from full participation at the University and the larger community including Indigenous Peoples, women, racialized persons, persons with disabilities and those who identify as 2SLGBTQIA+ (Two Spirit, lesbian, gay, bisexual, trans, questioning, intersex, asexual and other diverse sexual identities). All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

    The Rady Faculty of Health Sciences is committed to the social justice principles of equity, access & participation and to promoting opportunities in hiring, promotion and tenure (where applicable) for systemically marginalized groups who have been excluded from full participation at the University and the larger community including Indigenous Peoples, Black, racially marginalized communities, disabled persons and those who identify as 2SLGBTQIA+ (Two Spirit, lesbian, gay, bisexual, trans, questioning, intersex, asexual and other diverse sexual identities).

    An inclusive, open and diverse community is essential to excellence and fosters voices that have been ignored or discouraged. To address the Rady Faculty of Health Sciences commitment to equity, access and participation, and in recognition of the underrepresentation of members of historically and currently excluded groups, we take proactive measures including implicit bias training for all hiring panels. We strive for diversity and cultural safety throughout the hiring process (hiring panels, short-list of candidates, interviews). The University acknowledges the potential impact that Career Interruptions and Personal Circumstances can have on an applicant's record of research achievement. Measures will be taken to ensure that these leaves will be taken into careful consideration during the evaluation process.

    We encourage you to self-identify aspects of your identity that position you to bring currently under-represented viewpoints, expertise and forms of excellence to this role.

    If you require accommodation supports during the recruitment process, please contact or Please note this contact information is for accommodation reasons only.

    Application materials, including letters of reference, will be handled in accordance with the protection of privacy provision of The Freedom of Information and Protection of Privacy Act (Manitoba). Please note that curriculum vitae may be provided to participating members of the search process.

    Interested applicants should apply directly to Dr. Pearson ) with a cover letter and CV. Applications will be reviewed as they are received, and the search will continue until the position is filled.

    For further information about this position please contact: Dr. Pearson )

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