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    Principal Research Scientist - Hamilton, ON, Canada - Allergan

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    Description
    Principal Research Scientist I Chemistry
    Research & Development
    Analytical Research & Development

    AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow.

    We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio.

    Follow @abbvie onTwitter ,Facebook ,Instagram ,YouTube andLinkedIn .
    AbbVie (


    NYSE:
    ABBV) is a global, research-based biopharmaceutical company formed in 2013, following separation from Abbott.

    AbbVie combines the focus and passion of a leading-edge biotech with the expertise and capabilities of a long-established pharmaceutical leader, to develop and market advanced therapies that address some of the world's most complex and serious diseases.

    AbbVie employs approximately 50,000 people worldwide and markets medicines in more than 170 countries.

    AbbVie is seeking a Principal Research Scientist I to conduct process research and development of small molecules from pre-clinical through early clinical phases.

    The successful candidate will be responsible for setting project strategies, defining project responsibilities and timelines, providing leadership in a matrixed team setting and developing robust processes for cGMP manufacturing of AbbVie's small molecule and/or antibody-drug conjugate candidates.

    The successful candidate will conceive of and develop synthetic routes for preclinical (GLP tox) and first in human (FIH) clinical deliveries, develop manufacturing processes, demonstrate processes in the API Pilot Plant, and establish appropriate control strategies.

    The position involves multi-disciplinary interactions with organic chemists, analytical chemists, engineers, solid state scientists, drug product development, program management, external partners, etc.

    The selected candidate will collaborate with Discovery Teams, Development Sciences Core Teams, and Asset Strategy Teams to advance preclinical and clinical candidates.

    It is expected that the candidate will utilize their expertise across CMC disciplines to generate collaborations with drug product development and regulatory affairs to further program goals.

    The ideal candidate will have strong verbal and written communication skills, and will serve as the lead author on development reports and as a key contributor to regulatory filings.

    PhD in Chemistry with 6+ years of relevant experience or MS in Chemistry with 12+ years of relevant experience or BS in chemistry with 14+ years of relevant experience.

    Proven scientific leadership; The successful candidate will have a strong understanding of modern organic chemistry and mechanistic theory, control strategy development and regulatory starting material strategies.

    An understanding of global regulatory expectations and experience with authoring development reports and regulatory filings is highly desirable.

    Demonstrates creative 'out of the box' thinking to solve difficult technical problems and champion new strategies/technologies to achieve project goals.

    Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance.
    We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.
    This job is eligible to participate in our short-term incentiveprograms.

    AbbVie is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion.

    It is AbbVie's policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.

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