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    Development Intern - Hamilton, ON, Canada - Fusion Pharmaceuticals

    Fusion Pharmaceuticals
    Fusion Pharmaceuticals Hamilton, ON, Canada

    1 week ago

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    Description
    FUSN) is a clinical-stage oncology company focused on developing next-generation radiopharmaceuticals as precision medicines.

    In addition to a robust proprietary pipeline, Fusion has a collaboration with AstraZeneca to jointly develop novel targeted alpha therapies (TATs) and combination programs between Fusion's TATs and AstraZeneca's DNA Damage Response Inhibitors (DDRis) and immuno-oncology agents.

    Fusion has also entered into a collaboration with Merck to evaluate FPI-1434 in combination with Merck's KEYTRUDA (pembrolizumab) in patients with solid tumors expressing IGF-1R.

    To support Fusion's growing pipeline of TATs, the company has signed strategic actinium supply agreements with TRIUMF, Niowave, and BWXT Medical.

    Currently, Fusion relies on CDMOs for the scale up and production of its compounds, including its radiolabelled drug products, backed-up by a strong R&D team for the early development of manufacturing and analytical process.

    In addition, Fusion has recently completed the construction of a 27,000 sqf GMP production facility that aims to support clinical material production, in support of Fusion's clinical activities.

    Fusion Pharmaceuticals is opening the role of "Process Development Radiochemist" to support the design of manufacturing and analytical processes as well as the technology transfer, in-house and with CDMO partners.

    This role will report to the Process development manager.

    The successful candidate will bring a strong background in radiolabelling and radiometal chemistry, as well as knowledge in analytical method development.

    Execute the laboratory work and tasks related to the development of manufacturing and analytical processes for targeted alpha therapies.

    Analyze generated data and report outcomes to the project's teams.
    Support the Process Development team with technical activities related to processes development, validation, or qualification.

    MS with 5+ years of experience in product development and manufacturing; Advanced degree in organic or analytical chemistry, radiochemistry, radiopharmaceutical sciences, Pharmaceutical Science, Chemical Engineering, or related scientific discipline is a must.

    Experience in radiopharmaceuticals manufacturing and analytical methods development and validation is a must.
    Experience in process scale-up using automated synthesis unit is an asset.

    Strong interpersonal skills are required, and the successful candidate will work in a cross-functional team and will be expected to take a leadership position in key manufacturing projects.

    Meticulous, self-motivated, decisive, and independent with a willingness to work in a fast-paced start up environment.

    All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual, gender identity, national origin, disability, or status as a protected veteran.

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